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Article

DICER1 RNase IIIb domain mutations are infrequent in testicular germ cell tumours.

BMC research notes - 15 Oct 2012

de Boer Carmela M, Eini Ronak, Gillis Ad M, Stoop Hans, Looijenga Leendert H J, White Stefan J

Abstract excerpt

BACKGROUND: Testicular Germ Cell Tumours (TGCT) are the most frequently occurring malignancy in males from 15-45 years of age. They are derived from germ cells unable to undergo physiological maturation, although the genetic basis for this is poorly understood. A recent report showed that mutations in the RNase IIIb domain of DICER1, a micro-RNA (miRNA) processing enzyme, are common in non-epithelial ovarian...

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Source

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Identifiers

PMID: 23068969
DOI: 10.1186/1756-0500-5-569
PMCID: PMC3503615

Genes

DICER1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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DICER1 RNase IIIb domain mutations are infrequent in testicular germ cell tumours.PMID 23068969Read ↗

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