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[Ovarian Sertoli-Leydig cell tumors: DICER1 hotspot mutations and associated clinicopathological features].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 8 May 2020

Xiao Y X, Zhu X L, Bi R, Tu X Y, Cheng Y F, Chang B, Yu L, Huang D, Lu Y M, Shan L, Yang W T

Abstract excerpt

Objective: To investigate DICER1 hotspot mutations in ovarian Sertoli-Leydig cell tumor (SLCT) and its associated clinicopathological features. Methods: Forty-three SLCTs and 40 other sex cord-stromal tumors (SCSTs) diagnosed between 2010 and 2017 at Fudan University Shanghai Cancer Center were examined for somatic DICER1 hotspot mutations by Sanger sequencing. The associations between mutation status and...

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PMID: 32392927
DOI: 10.3760/cma.j.cn112151-20190826-00466

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