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Article

DICER1 hot-spot mutations in ovarian gynandroblastoma.

Histopathology - 1 Aug 2018

Wang Yemin, Karnezis Anthony N, Magrill Jamie, Tessier-Cloutier Basile, Lum Amy, Senz Janine, Gilks C Blake, McCluggage W Glenn, Huntsman David G, Kommoss Friedrich

Abstract excerpt

AIMS: Gynandroblastoma is a rare ovarian sex cord-stromal tumour characterised by the presence of both male (Sertoli and/or Leydig cells) and female (granulosa cells) components. We investigated the mutational status of DICER1, FOXL2 and AKT1 genes at hot-spot regions that are known to be the key driving events in the development of Sertoli-Leydig cell tumour (SLCT), adult granulosa cell tumour (aGCT) and...

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Source

Identifiers

PMID: 29660837
DOI: 10.1111/his.13630

Genes

DICER1
FOXL2
AKT1

Provenance

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DICER1 hot-spot mutations in ovarian gynandroblastoma.PMID 29660837Read ↗

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