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Article

Genetic studies on the APOA1-C3-A5 gene cluster in Asian Indians with premature coronary artery disease.

Lipids in health and disease - 19 Sept 2008

Shanker Jayashree, Perumal Ganapathy, Rao Veena S, Khadrinarasimhiah Natesha B, John Shibu, Hebbagodi Sridhara, Mukherjee Manjari, Kakkar Vijay V

Abstract excerpt

BACKGROUND: The APOA1-C3-A5 gene cluster plays an important role in the regulation of lipids. Asian Indians have an increased tendency for abnormal lipid levels and high risk of Coronary Artery Disease (CAD). Therefore, the present study aimed to elucidate the relationship of four single nucleotide polymorphisms (SNPs) in the Apo11q cluster, namely the -75G>A, +83C>T SNPs in the APOA1 gene, the Sac1 SNP in the...

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Source

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Identifiers

PMID: 18801202
DOI: 10.1186/1476-511X-7-33
PMCID: PMC2556320

Genes

CAD
APOA1
APOC3
APOA5

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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