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Article

Genetic variants in the integrin gene predicted microRNA-binding sites were associated with the risk of prostate cancer.

Molecular carcinogenesis - 1 Apr 2014

Liu Jiaming, Huang Jin, He Yazhou, Liu Jinnan, Liao Banghua, Liao Ga

Abstract excerpt

microRNAs (miRNA) silence target genes through Watson-Crick based binding to the 3'untranslated regions (3'UTR). Thus, polymorphisms in the miRNA-binding sites may disrupt this process and play a potential role in cancer pathogenesis. Integrins have been implicated in the genesis and development of many tumors. This study was designed to evaluate the association between five SNP loci in predicted miRNA-binding...

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PMID: 23065910
DOI: 10.1002/mc.21973

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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