Article
Association between polymorphisms of microRNA-binding sites in integrin genes and gastric cancer in Chinese Han population.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2015
Song Xingbo, Zhong Huiyu, Zhou Juan, Hu Xuejiao, Zhou Yi, Ye Yuanxin, Lu Xiaojun, Wang Jun, Ying Binwu, Wang Lanlan
Abstract excerpt
Highly elevated expression of integrin has been observed in a variety of malignant tumors. Single nucleotide polymorphisms (SNPs) in the microRNA-binding sites in the 3' UTR region of target genes may result in the level change of target gene expression and subsequently susceptible to diseases, including cancer. In this study, we aimed to investigate the association between polymorphisms of microRNA-binding sites...
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