Article
Association of the PTEN IVS4 (rs3830675) gene polymorphism with reduced risk of cancer: evidence from a meta-analysis.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2015
Mandal Raju K, Akhter Naseem, Irshad Mohammad, Panda Aditya K, Ali Arif, Haque Shafiul
Abstract excerpt
PTEN (phosphatase and tensin homologue), as a tumor suppressor gene, plays a significant role in regulating cell growth, proliferation, and apoptosis. Results from published studies for association between the PTEN IVS4 I/D (rs3830675) polymorphism and cancer risk are inconsistent and inconclusive. We therefore conducted a meta-analysis to evaluate the potential association between PTEN IVS4 I/D polymorphism and...
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