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Article

PTEN expression and mutation in colorectal carcinomas.

Oncology reports - 1 Oct 2009

Li Xiao-Han, Zheng Hua-Chuan, Takahashi Hiroyuki, Masuda Shinji, Yang Xiang-Hong, Takano Yasuo

Abstract excerpt

The phosphatase and tensin homolog deleted on chromosome 10 (PTEN) tumor suppressor is a phosphatase that antagonizes the phosphoinositol-3-kinase/AKT signaling pathway and suppresses cell survival as well as cell proliferation. To investigate the molecular role of PTEN expression and mutation in colorectal carcinomas, we performed immunohistochemistry to detect PTEN expression on tissue microarray containing...

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Source

Identifiers

PMID: 19724853
DOI: 10.3892/or_00000497

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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