Article
Common variation in with no-lysine kinase 1 (WNK1) and blood pressure responses to dietary sodium or potassium interventions- family-based association study.
Circulation journal : official journal of the Japanese Circulation Society - 1 Jan 2013
Liu Fuqiang, Zheng Shuhui, Mu Jianjun, Chu Chao, Wang Lan, Wang Yang, Xiao Hongyu, Wang Dan, Cao Yu, Ren Keyu, Liu Enqi, Yuan Zuyi
Abstract excerpt
BACKGROUND: Common variations in the gene with no-lysine kinase 1 (WNK1) are associated with hypertension, but because of gene-environment interaction, it is difficult to fully identify the genetic contribution of WNK1 gene polymorphism to blood pressure (BP) variability. The aim of this study was to identify the effect of common WNK1 variants on the shift of BP during strict dietary interventions of salt or...
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