Article
Common variation in the WNK1 gene and blood pressure in childhood: the Avon Longitudinal Study of Parents and Children.
Hypertension (Dallas, Tex. : 1979) - 1 Nov 2008
Tobin Martin D, Timpson Nicholas J, Wain Louise V, Ring Susan, Jones Louise R, Emmett Pauline M, Palmer Thomas M, Ness Andrew R, Samani Nilesh J, Smith George Davey, Burton Paul R
Abstract excerpt
WNK1 gene variants have been associated with adult blood pressure. We aimed to investigate relationships between WNK1 variants and blood pressure, as well as blood pressure change with age, in a longitudinal childhood study. Associations between single nucleotide polymorphisms in WNK1 and blood pressure and the rate of blood pressure change between 7 and 11 years were examined in the Avon Longitudinal Study of...
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