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Article

Variations in the WNK1 gene modulates the effect of dietary intake of sodium and potassium on blood pressure determination.

Journal of human genetics - 1 Aug 2009

Osada Yuko, Miyauchi Rie, Goda Toshinao, Kasezawa Nobuhiko, Horiike Hiromi, Iida Mariko, Sasaki Satoshi, Yamakawa-Kobayashi Kimiko

Abstract excerpt

WNK lysine-deficient protein kinase 1 (WNK1) is a member of the WNK family of serine/threonine kinases with no lysine (K), and these kinases have been implicated as important modulators of salt homeostasis in the kidney. It is well known that high dietary sodium and low dietary potassium have been implicated in the etiology of increased blood pressure. However, the blood pressure response to dietary sodium and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

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Source

Identifiers

PMID: 19609280
DOI: 10.1038/jhg.2009.64

Genes

WNK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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