Article
Genome-wide association study identifies 8 novel loci associated with blood pressure responses to interventions in Han Chinese.
Circulation. Cardiovascular genetics - 1 Dec 2013
He Jiang, Kelly Tanika N, Zhao Qi, Li Hongfan, Huang Jianfeng, Wang Laiyuan, Jaquish Cashell E, Sung Yun Ju, Shimmin Lawrence C, Lu Fanghong, Mu Jianjun, Hu Dongsheng, Ji Xu, Shen Chong, Guo Dongshuang, Ma Jixiang, Wang Renping, Shen Jinjin, Li Shengxu, Chen Jing, Mei Hao, Chen Chung-Shiuan, Chen Shufeng, Chen Jichun, Li Jianxin, Cao Jie, Lu Xiangfeng, Wu Xigui, Rice Treva K, Gu C Charles, Schwander Karen, Hamm L Lee, Liu Depei, Rao Dabeeru C, Hixson James E, Gu Dongfeng
Abstract excerpt
BACKGROUND: Blood pressure (BP) responses to dietary sodium and potassium intervention and cold pressor test vary considerably among individuals. We aimed to identify novel genetic variants influencing individuals' BP responses to dietary intervention and cold pressor test. METHODS AND RESULTS: We conducted a genome-wide association study of BP responses in 1881 Han Chinese and de novo genotyped top findings in...
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