Article
The Relationship between Mitochondrial Genome Mutations in Monocytes and the Development of Obesity and Coronary Heart Disease.
Frontiers in bioscience (Scholar edition) - 13 Mar 2024
Tolstik Taisiya V, Kirichenko Tatiana V, Bogatyreva Anastasia I, Markina Yuliya V, Kalmykov Vladislav A, Markin Alexander M
Abstract excerpt
BACKGROUND: Metabolic disorders, including obesity, are often accompanied by an increased risk of cardiovascular complications. Monocytes are the common link between obesity and cardiovascular diseases (CVDs). The bias of innate cellular immunity towards pro-inflammatory activation stimulates the development of diseases associated with chronic inflammation, in particular metabolic disorders, including obesity, as...
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