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Article

Pulse-chase analysis of the in vivo assembly of the bacteriophage T4 tail.

Journal of molecular biology - 17 Mar 2000

Ferguson P L, Coombs D H

Abstract excerpt

The in vivo assembly pathway of the complex tail of bacteriophage T4 virus was determined using pulse-chase analysis as a non-invasive alternative to the in vitro experiments previously used to map assembly. Bacteriophage T4 mutants defective in head assembly were used to infect cultures of Escherichia coli in order to study tail assembly in isolation. Beginning with the onset of late protein synthesis, the...

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Identifiers

PMID: 10704310
DOI: 10.1006/jmbi.2000.3551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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