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Article

Fine-mapping of restless legs locus 4 (RLS4) identifies a haplotype over the SPATS2L and KCTD18 genes.

Journal of molecular neuroscience : MN - 1 Mar 2013

Pichler Irene, Schwienbacher Christine, Zanon Alessandra, Fuchsberger Christian, Serafin Alice, Facheris Maurizio F, Marroni Fabio, Pattaro Cristian, Shen Yiping, Tellgren-Roth Christian, Gyllensten Ulf, Gusella James F, Hicks Andrew A, Pramstaller Peter P

Abstract excerpt

Restless legs syndrome (RLS) is a sleep-related movement disorder that affects up to 15 % of the population. Linkage studies have identified several genomic loci in single families (12q, 14q, 9p, 2q, 20p and 16p, respectively). However, confirmation of these loci has not always been achieved, and causative mutations have not yet been identified. The locus on chromosome 2q33 (RLS4) was identified in two South...

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Identifiers

PMID: 23054586
DOI: 10.1007/s12031-012-9891-5

Genes

KCTD18

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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