Article
MDR1 genetic polymorphisms and comparison of MDR1 haplotype profiles in Korean and Vietnamese populations.
Therapeutic drug monitoring - 1 Aug 2005
Lee Sang Seop, Kim So-Young, Kim Woo-Young, Thi-Le Huong, Yoon Young-Ran, Yea Sung Su, Shin Jae-Gook
Abstract excerpt
Two representative genetic variants of the MDR1 gene, 3435C>T and 2677G>T/A, show wide interethnic differences in its genetic polymorphism. In this study, the authors evaluated the genetic polymorphisms of MDR1 and directly compared MDR1 haplotype profiles of the Korean and Vietnamese populations. The 3435C>T and 2677G>T/A variations were analyzed in 632 Koreans and 142 Vietnamese using pyrosequencing. The...
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