Article
DSPP Is Essential for Normal Development of the Dental-Craniofacial Complex.
Journal of dental research - 1 Mar 2016
Chen Y, Zhang Y, Ramachandran A, George A
Abstract excerpt
The craniofacial skeleton is derived from both neural crest cells and mesodermal cells; however, the majority of the bone, cartilage, and connective tissue is derived from the neural crest. Dentin sialophosphoprotein (DSPP) is a precursor protein that is expressed by the connective tissues of the craniofacial skeleton, namely, bone and dentin with high expression levels in the dentin matrix. Gene ablation studies...
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