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Article

Haplotypes with copy number and single nucleotide polymorphisms in CYP2A6 locus are associated with smoking quantity in a Japanese population.

PloS one - 1 Jan 2012

Kumasaka Natsuhiko, Aoki Masayuki, Okada Yukinori, Takahashi Atsushi, Ozaki Kouichi, Mushiroda Taisei, Hirota Tomomitsu, Tamari Mayumi, Tanaka Toshihiro, Nakamura Yusuke, Kamatani Naoyuki, Kubo Michiaki

Abstract excerpt

Smoking is a major public health problem, but the genetic factors associated with smoking behaviors are not fully elucidated. Here, we have conducted an integrated genome-wide association study to identify common copy number polymorphisms (CNPs) and single nucleotide polymorphisms (SNPs) associated with the number of cigarettes smoked per day (CPD) in Japanese smokers (N = 17,158). Our analysis identified a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23049750
DOI: 10.1371/journal.pone.0044507
PMCID: PMC3458030

Genes

CNP
CPD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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