Article
Genetic polymorphisms in CYP2A6 are associated with a risk of cigarette smoking and predispose to smoking at younger ages.
Gene - 10 Sept 2017
Pérez-Rubio Gloria, López-Flores Luis Alberto, Ramírez-Venegas Alejandra, Noé-Díaz Valeri, García-Gómez Leonor, Ambrocio-Ortiz Enrique, Sánchez-Romero Candelaria, Hernández-Zenteno Rafael De Jesús, Sansores Raúl Humberto, Falfán-Valencia Ramcés
Abstract excerpt
Nicotine is the main component of cigarettes that causes addiction, which is considered a complex disease, and genetic factors have been proposed to be involved in the development of addiction. The CYP2A6 gene encodes the main enzyme responsible for nicotine metabolism. Depending on the study population, different genetic variants of CYP2A6 associated with cigarette smoking have been described. Therefore, we...
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