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Article

Neurogenin2 regulates the initial axon guidance of cortical pyramidal neurons projecting medially to the corpus callosum.

Neural development - 24 Aug 2011

Hand Randal, Polleux Franck

Abstract excerpt

BACKGROUND: The formation of the mammalian central nervous system requires the establishment of complex neural circuits between a diverse array of neuronal subtypes. Here we report that the proneural transcription factor Neurogenin2 (Ngn2) is crucial for the proper specification of cortical axon projections. RESULTS: The genetic loss of Ngn2 in mice results in fewer callosal axons projecting towards the midline...

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Source

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Identifiers

PMID: 21864333
DOI: 10.1186/1749-8104-6-30
PMCID: PMC3174110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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