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Article

Genetic dissection of midbrain dopamine neuron development in vivo.

Developmental biology - 15 Dec 2012

Ellisor Debra, Rieser Caroline, Voelcker Bettina, Machan Jason T, Zervas Mark

Abstract excerpt

Midbrain dopamine (MbDA) neurons are partitioned into medial and lateral cohorts that control complex functions. However, the genetic underpinnings of MbDA neuron heterogeneity are unclear. While it is known that Wnt1-expressing progenitors contribute to MbDA neurons, the role of Wnt1 in MbDA neuron development in vivo is unresolved. We show that mice with a spontaneous point mutation in Wnt1 have a unique...

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Identifiers

PMID: 23041116
DOI: 10.1016/j.ydbio.2012.09.019
PMCID: PMC3502751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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