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Article

Detection of IDH1 mutation in the plasma of patients with glioma.

Neurology - 16 Oct 2012

Boisselier Blandine, Gállego Pérez-Larraya Jaime, Rossetto Marta, Labussière Marianne, Ciccarino Pietro, Marie Yannick, Delattre Jean-Yves, Sanson Marc

Abstract excerpt

OBJECTIVE: The IDH1(R132H) mutation is both a strong prognostic predictor and a diagnostic hallmark of gliomas and therefore has major clinical relevance. Here, we developed a new technique to detect the IDH1(R132H) mutation in the plasma of patients with glioma. METHODS: Small-size DNA (150-250 base pairs) was extracted from the plasma of 31 controls and 80 patients with glioma with known IDH1(R132H) status and...

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Source

Identifiers

PMID: 23035067
DOI: 10.1212/WNL.0b013e31826e9b0a

Genes

IDH1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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