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Article

DNA typing for class II HLA antigens with allele-specific or group-specific amplification. III. Typing for 24 alleles of HLA-DP.

Human immunology - 1 Jan 1991

Fernandez-Vina M, Moraes M E, Stastny P

Abstract excerpt

The second exon of HLA-DPB includes five polymorphic segments with extensive sharing of sequences between alleles. In order to facilitate assignment of specificities in heterozygous individuals, we have used group-specific amplification of two nonoverlapping sets of DPB alleles (here called group A and group B) with especially designed primers. Group A and group B polymerase chain reaction products were...

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PMID: 2001976
DOI: 10.1016/0198-8859(91)90072-h

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