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Article

Opc expression, LPS immunotype switch and pilin conversion contribute to serum resistance of unencapsulated meningococci.

PloS one - 1 Jan 2012

Hubert Kerstin, Pawlik Marie-Christin, Claus Heike, Jarva Hanna, Meri Seppo, Vogel Ulrich

Abstract excerpt

Neisseria meningitidis employs polysaccharides and outer membrane proteins to cope with human serum complement attack. To screen for factors influencing serum resistance, an assay was developed based on a colorimetric serum bactericidal assay. The screening used a genetically modified sequence ty...

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Identifiers

PMID: 23028802
DOI: 10.1371/journal.pone.0045132
PMCID: PMC3447861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23028802-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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