Article
Sequence, distribution and chromosomal context of class I and class II pilin genes of Neisseria meningitidis identified in whole genome sequences.
BMC genomics - 1 Apr 2014
Wörmann Mirka E, Horien Corey L, Bennett Julia S, Jolley Keith A, Maiden Martin C J, Tang Christoph M, Aho Ellen L, Exley Rachel M
Abstract excerpt
BACKGROUND: Neisseria meningitidis expresses type four pili (Tfp) which are important for colonisation and virulence. Tfp have been considered as one of the most variable structures on the bacterial surface due to high frequency gene conversion, resulting in amino acid sequence variation of the major pilin subunit (PilE). Meningococci express either a class I or a class II pilE gene and recent work has indicated...
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