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Article

A generic mechanism in<i>Neisseria meningitidis</i>for enhanced resistance against bactericidal antibodies

26 May 2008

Abstract excerpt

The presence of serum bactericidal antibodies is a proven correlate of protection against systemic infection with the important human pathogen Neisseria meningitidis. We have identified three serogroup C N. meningitidis (MenC) isolates recovered from patients with invasive meningococcal disease that resist killing by bactericidal antibodies induced by the MenC conjugate vaccine. None of the patients had received...

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PMID: 18504306
DOI: 10.1084/jem.20072577

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