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Article

Opc- and pilus-dependent interactions of meningococci with human endothelial cells: molecular mechanisms and modulation by surface polysaccharides.

Molecular microbiology - 1 Nov 1995

Virji M, Makepeace K, Peak I R, Ferguson D J, Jennings M P, Moxon E R

Abstract excerpt

The interplay between four surface-expressed virulence factors of Neisseria meningitidis (pili, Opc, capsule and lipopolysaccharide (LPS)) in host cell adhesion and invasion was examined using derivatives of a serogroup B strain, MC58, created by mutation (capsule, Opc) and selection of variants. To examine the role of Opc and of additional expression of pili, bacteria lacking the expression of Opa proteins were...

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Identifiers

PMID: 8817495
DOI: 10.1111/j.1365-2958.1995.mmi_18040741.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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