Article
Attachment and invasion of Neisseria meningitidis to host cells is related to surface hydrophobicity, bacterial cell size and capsule.
PloS one - 1 Jan 2013
Bartley Stephanie N, Tzeng Yih-Ling, Heel Kathryn, Lee Chiang W, Mowlaboccus Shakeel, Seemann Torsten, Lu Wei, Lin Ya-Hsun, Ryan Catherine S, Peacock Christopher, Stephens David S, Davies John K, Kahler Charlene M
Abstract excerpt
We compared exemplar strains from two hypervirulent clonal complexes, strain NMB-CDC from ST-8/11 cc and strain MC58 from ST-32/269 cc, in host cell attachment and invasion. Strain NMB-CDC attached to and invaded host cells at a significantly greater frequency than strain MC58. Type IV pili retained the primary role for initial attachment to host cells for both isolates regardless of pilin class and glycosylation...
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