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Article

MAP kinase genes and colon and rectal cancer.

Carcinogenesis - 1 Dec 2012

Slattery Martha L, Lundgreen Abbie, Wolff Roger K

Abstract excerpt

Mitogen-activated protein kinase (MAPK) pathways regulate many cellular functions including cell proliferation, differentiation, migration and apoptosis. We evaluate genetic variation in the c-Jun-N-terminal kinases, p38, and extracellular regulated kinases 1/2 MAPK-signaling pathways and colon and rectal cancer risk using data from population-based case-control studies (colon: n = 1555 cases, 1956 controls;...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23027623
DOI: 10.1093/carcin/bgs305
PMCID: PMC3510742

Genes

DUSP1
DUSP2
MAPK8
DUSP4
DUSP6
DUSP7
KRAS
MAPK1
MAPK12
MAPK14
MAPK3
RAF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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