Article
DNA repair gene variants in relation to overall cancer risk: a population-based study.
Carcinogenesis - 1 Jan 2013
Alberg Anthony J, Jorgensen Timothy J, Ruczinski Ingo, Wheless Lee, Shugart Yin Yao, Berthier-Schaad Yvette, Kessing Bailey, Hoffman-Bolton Judith, Helzlsouer Kathy J, Kao W H Linda, Francis Lesley, Alani Rhoda M, Smith Michael W, Strickland Paul T
Abstract excerpt
The hypothesis that germ-line polymorphisms in DNA repair genes influence cancer risk has previously been tested primarily on a cancer site-specific basis. The purpose of this study was to test the hypothesis that DNA repair gene allelic variants contribute to globally elevated cancer risk by measuring associations with risk of all cancers that occurred within a population-based cohort. In the CLUE II cohort...
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