XPG rs17655 G>C polymorphism associated with cancer risk: evidence from 60 studies.

doi:10.18632/aging.101448

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XPG rs17655 G>C polymorphism associated with cancer risk: evidence from 60 studies.

Aging - 20 May 2018

Zhao Jie, Chen Shanshan, Zhou Haixia, Zhang Ting, Liu Yang, He Jing, Zhu Jinhong, Ruan Jichen

Abstract excerpt

Xeroderma pigmentosum group G (XPG), a key component in nucleotide excision repair pathway, functions to cut DNA lesions during DNA repair. Genetic variations that alter DNA repair gene expression or function may decrease DNA repair ability and impair genome integrity, thereby predisposing to cancer. The association between XPG rs17655 G>C polymorphism and cancer risk has been investigated extensively, but the...

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PMID: 29779017
DOI: 10.18632/aging.101448
PMCID: PMC5990387

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