Article
A population-based study of DNA repair gene variants in relation to non-melanoma skin cancer as a marker of a cancer-prone phenotype.
Carcinogenesis - 1 Sept 2012
Ruczinski Ingo, Jorgensen Timothy J, Shugart Yin Yao, Schaad Yvette Berthier, Kessing Bailey, Hoffman-Bolton Judith, Helzlsouer Kathy J, Kao W H Linda, Wheless Lee, Francis Lesley, Alani Rhoda M, Strickland Paul T, Smith Michael W, Alberg Anthony J
Abstract excerpt
For unknown reasons, non-melanoma skin cancer (NMSC) is associated with increased risk of other malignancies. Focusing solely on DNA repair or DNA repair-related genes, this study tested the hypothesis that DNA repair gene variants contribute to the increased cancer risk associated with a personal history of NMSC. From the parent CLUE II cohort study, established in 1989 in Washington County, MD, the study...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.