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Article

Cancer risk in mismatch repair gene mutation carriers.

Familial cancer - 1 Jan 2001

Watson P, Lynch H T

Abstract excerpt

Optimally accurate and valid estimates of cancer risk in genetically- defined subgroups requires population-based research. For rare genetic traits, very large studies are needed. Such is the case in hereditary nonpolyposis colorectal cancer syndrome (HNPCC), caused by mutations in mismatch repair (MMR) genes. A potentially more efficient approach is genotyped-proband design (GPD), in which probands are genotyped...

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Identifiers

PMID: 14574017
DOI: 10.1023/a:1011590617833

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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