Article
Analysis of liver lymphoid cell subsets pre- and post-in vivo administration of human recombinant interleukin 2 in a C57BL/6 murine system.
Cancer research - 1 Mar 1990
Lafreniere R, Borkenhagen K, Bryant L D, Anton A R, Chung A, Poon M C
Abstract excerpt
The systemic administration of high dose recombinant interleukin 2 (RIL-2) can mediate significant reductions in the number of hepatic metastases in a murine system. This effect is sensitive to host irradiation. Both large granular (LGLs) and small (SLs) lymphocytes have been implicated as the ce...
Topics
- Animals
- Antigens, Surface
- Cell Separation
- Cytotoxicity, Immunologic
- Drug Administration Schedule
- Humans
- Interleukin-2
- Liver
- Lymphocytes
- Mice
- Mice, Inbred C57BL
- Organ Size
- Phenotype
- Recombinant Proteins