Functional and phenotypic characteristics of recombinant interleukin-2 or T-cell growth factor-activated splenic lymphoid cells from patients with gastric or hepatocellular carcinoma.

doi:10.1002/1097-0142(19900901)66:5<923::aid-cncr2820660518>3.0.co;2-r

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Article

Functional and phenotypic characteristics of recombinant interleukin-2 or T-cell growth factor-activated splenic lymphoid cells from patients with gastric or hepatocellular carcinoma.

Cancer - 1 Sept 1990

Ebihara T, Fukao K, Koyama S

Abstract excerpt

Fourteen days' culture of human spleen cells with recombinant interleukin-2 (rIL-2) or T-cell growth factor (TCGF) results in the generation of lymphokine-activated killer (LAK) effector cells that have the unique property of lysing natural killer (NK)-resistant human tumor cells, Daudi, and NK-sensitive K562 cells. LAK cells were generated from patients with advanced cancer or liver cirrhosis. The splenic...

Topics

Adult
Aged
Antigens, Differentiation, T-Lymphocyte
CD4 Antigens
CD8 Antigens
Carcinoma, Hepatocellular
Female
Humans
Immunity, Cellular
Interleukin-2
Killer Cells, Lymphokine-Activated

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Liver Neoplasms

Lymphocyte Activation

Male

Middle Aged

Phenotype

Spleen

Stomach Neoplasms

Source

Open in PubMed

Identifiers

PMID: 2167147
DOI: 10.1002/1097-0142(19900901)66:5<923::aid-cncr2820660518>3.0.co;2-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2167147-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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