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Article

Secondary structure and the role in translation initiation of the 5'-terminal region of p53 mRNA.

Biochemistry - 23 Aug 2011

Błaszczyk Leszek, Ciesiołka Jerzy

Abstract excerpt

The p53 protein is one of the major factors involved in cell cycle control, DNA repair, and induction of apoptosis. We determined the secondary structure of the 5'-terminal region of p53 mRNA that includes two major translation initiation codons AUG1 and AUG2, responsible for the synthesis of p53 and its N-truncated isoform ΔN-p53. It turned out that a part of the coding sequence was involved in the folding of...

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PMID: 21770379
DOI: 10.1021/bi200659b

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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