Article
Functionally significant nicotine acetylcholine receptor subunit α5 promoter haplotypes are associated with susceptibility to lung cancer in Chinese.
Cancer - 15 Oct 2011
Zheng Xia, Duan Wenyuan, Xu Jing, Nie Chenxia, Yang Zhangmin, Wang Hongyan, Wang Weimin, Lu Daru
Abstract excerpt
BACKGROUND: Although recent genome-wide association studies have been conducted to reveal the relation between variations in the α5 nicotinic receptor subunit and lung cancer in European and American populations, to the authors' knowledge, no definite information on the role of nicotine acetylcholine receptor subunit α5 (CHRNA5) in lung cancer risk has been obtained in a Chinese population. METHODS: To test this...
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