Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phosphorylated tubulin adaptor protein CRMP-2 as prognostic marker and candidate therapeutic target for NSCLC.

International journal of cancer - 1 May 2013

Oliemuller Erik, Peláez Rafael, Garasa Saray, Pajares María J, Agorreta Jackeline, Pío Rubén, Montuenga Luis M, Teijeira Alvaro, Llanos Susana, Rouzaut Ana

Abstract excerpt

Collapsin response mediator protein-2 (CRMP-2) is the first described and most studied member of a family of proteins that mediate the addition of tubulin dimers to the growing microtubule. CRMPs have mainly been studied in the nervous system, but recently, they have been described in other tissues where they participate in vesicle transport, migration and mitosis. In this work, we aimed at studying the role of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Adenosquamous
Share to Carcinoma, Large Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescent Antibody Technique

Share to Immunoenzyme Techniques

Share to Immunoprecipitation

Share to Intercellular Signaling Peptides and Proteins

Share to Microtubules

Share to Spindle Apparatus

Source

Identifiers

PMID: 23023514
DOI: 10.1002/ijc.27881

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phosphorylated tubulin adaptor protein CRMP-2 as prognostic marker and candidate therapeutic target for NSCLC.PMID 23023514Read ↗

A phosphorylation cluster in the chromatin-binding region regulates chromosome association of LAP2alpha.Semantic proximity Read ↗

Characterization of mitosis-specific phosphorylation of tumor-associated microtubule-associated protein.Semantic proximity Read ↗

Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones.Semantic proximity Read ↗

Mitotic spindle organizing protein 2A (MZT2A) promotes NSCLC cell viability and invasion by upregulating galectin-3-binding protein (LGALS3BP), increases AKT phosphorylation via the MOZART2 domain and predicts poor NSCLC prognosisSemantic proximity Read ↗

AURKA, DLGAP5, TPX2, KIF11 and CKAP5: Five specific mitosis-associated genes correlate with poor prognosis for non-small cell lung cancer patientsSemantic proximity Read ↗

Proteome and behavioral alterations in phosphorylation-deficient mutant Collapsin Response Mediator Protein2 knock-in mice.Semantic proximity Read ↗

Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic deathSemantic proximity Read ↗

<scp>GLTSCR</scp>2 is an upstream negative regulator of nucleophosmin in cervical cancerSemantic proximity Read ↗

Collapsin Response Mediator Protein - 2 Hyperphosphorylation: Hallmark for contributing to various Neurodegenerative DisordersSemantic proximity Read ↗

Characterization of a Novel 350-Kilodalton Nuclear Phosphoprotein That Is Specifically Involved in Mitotic-Phase ProgressionSemantic proximity Read ↗

S-phase kinase-associated protein 2 positively controls mitotic arrest deficient 2 in lung cancer cellsSemantic proximity Read ↗

KIF2C exerts an oncogenic role in nonsmall cell lung cancer and is negatively regulated by miR‐325‐3pSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.