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Mitotic spindle organizing protein 2A (MZT2A) promotes NSCLC cell viability and invasion by upregulating galectin-3-binding protein (LGALS3BP), increases AKT phosphorylation via the MOZART2 domain and predicts poor NSCLC prognosis

2020-11-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Mitotic spindle organizing protein 2A (MZT2A) is localized at the centrosome and regulates microtubule nucleation activity in cells. This study assessed the role of MZT2A in non-small cell lung cancer (NSCLC). <bold>Methods</bold>: Differential MZT2A expression was bioinformatically assessed using the Cancer Genome Atlas database, Gene Expression Profiling Inter...

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Literature Corpus work
eb8d6397-07a1-57a9-b46a-d598fce534be
DOI
10.21203/rs.3.rs-103648/v1
Open publication

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Mitotic spindle organizing protein 2A (MZT2A) promotes NSCLC cell viability and invasion by upregulating galectin-3-binding protein (LGALS3BP), increases AKT phosphorylation via the MOZART2 domain and predicts poor NSCLC prognosisDOI 10.21203/rs.3.rs-103648/v1
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