Article
Clonal allelic predetermination of immunoglobulin-κ rearrangement.
Nature - 25 Oct 2012
Farago Marganit, Rosenbluh Chaggai, Tevlin Maya, Fraenkel Shira, Schlesinger Sharon, Masika Hagit, Gouzman Masha, Teng Grace, Schatz David, Rais Yoach, Hanna Jacob H, Mildner Alexander, Jung Steffen, Mostoslavsky Gustavo, Cedar Howard, Bergman Yehudit
Abstract excerpt
Although most genes are expressed biallelically, a number of key genomic sites--including immune and olfactory receptor regions--are controlled monoallelically in a stochastic manner, with some cells expressing the maternal allele and others the paternal allele in the target tissue. Very little i...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.