Article
The p23 molecular chaperone and GCN5 acetylase jointly modulate protein-DNA dynamics and open chromatin status.
Molecular cell - 9 Nov 2012
Zelin Elena, Zhang Yang, Toogun Oyetunji A, Zhong Sheng, Freeman Brian C
Abstract excerpt
Cellular processes function through multistep pathways that are reliant on the controlled association and disassociation of sequential protein complexes. While dynamic action is critical to propagate and terminate work, the mechanisms used to disassemble biological structures are not fully understood. Here we show that the p23 molecular chaperone initiates disassembly of protein-DNA complexes and that the GCN5...
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