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Article

Genome-wide analysis of intracellular pH reveals quantitative control of cell division rate by pH(c) in Saccharomyces cerevisiae.

Genome biology - 10 Sept 2012

Orij Rick, Urbanus Malene L, Vizeacoumar Franco J, Giaever Guri, Boone Charles, Nislow Corey, Brul Stanley, Smits Gertien J

Abstract excerpt

BACKGROUND: Because protonation affects the properties of almost all molecules in cells, cytosolic pH (pH(c)) is usually assumed to be constant. In the model organism yeast, however, pH(c) changes in response to the presence of nutrients and varies during growth. Since small changes in pH(c) can lead to major changes in metabolism, signal transduction, and phenotype, we decided to analyze pH(c) control. RESULTS:...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23021432
DOI: 10.1186/gb-2012-13-9-r80
PMCID: PMC3506951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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