Article
Association study identifying polymorphisms in CD47 and other extracellular matrix pathway genes as putative prognostic markers for colorectal cancer.
International journal of colorectal disease - 1 Feb 2013
Lascorz Jesús, Bevier Melanie, V Schönfels Witigo, Kalthoff Holger, Aselmann Heiko, Beckmann Jan, Egberts Jan, Buch Stephan, Becker Thomas, Schreiber Stefan, Hampe Jochen, Hemminki Kari, Schafmayer Clemens, Försti Asta
Abstract excerpt
PURPOSE: We identified recently the extracellular matrix (ECM) receptor interaction pathway as a consistently overrepresented category among gene expression profiling studies on colorectal cancer (CRC) prognosis. METHODS: Putative regulatory single nucleotide polymorphisms (SNPs) in genes from the ECM pathway were genotyped in 613 CRC patients from Northern Germany (PopGen cohort) and tested for association with...
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