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Article

Functional Genetic Variations at the microRNA Binding-Site in the CD44 Gene Are Associated with Risk of Colorectal Cancer in Chinese Populations.

PloS one - 1 Jan 2015

Wu Xiao-Min, Yang Hong-Guo, Zheng Bo-An, Cao Hong-Feng, Hu Zhi-Ming, Wu Wei-Ding

Abstract excerpt

CD44 as one of the most putative stem cell markers plays a key role in many cellular processes, including cancer cell growth and migration. Functional single nucleotide polymorphisms (SNPs) of CD44 may modulate its gene functions and thus cancer risk. In the current study, we investigated if polymorphisms in the 3'-untranslated region (UTR) of CD44 are associated with increased susceptibility to colorectal cancer...

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Identifiers

PMID: 26010608
DOI: 10.1371/journal.pone.0127557
PMCID: PMC4444206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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