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Article

CD44 rs13347 C>T polymorphism predicts breast cancer risk and prognosis in Chinese populations.

Breast cancer research : BCR - 12 Jul 2012

Jiang Lan, Deng Jieqiong, Zhu Xun, Zheng Jian, You Yonghe, Li Na, Wu Hongchun, Lu Jiachun, Zhou Yifeng

Abstract excerpt

INTRODUCTION: It has been demonstrated that the interplay of adhesion molecule CD44 and its ligands can regulate cancer cell proliferation, migration and invasion, as well as tumor-associated angiogenesis and is related to breast cancer patient survival. In this two-stage, case control study, we determined whether common functional tagSNPs (single nucleotide polymorphisms) are associated with breast cancer risk...

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PMID: 22788972
DOI: 10.1186/bcr3225
PMCID: PMC3680922

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