Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A subset of genetic susceptibility variants for colorectal cancer also has prognostic value.

The pharmacogenomics journal - 1 Apr 2016

Noci S, Dugo M, Bertola F, Melotti F, Vannelli A, Dragani T A, Galvan A

Abstract excerpt

We investigated the possible influence of 86 single-nucleotide polymorphisms (SNPs), known to associate with the risk of colorectal cancer (CRC), on overall survival and time to recurrence (TTR) in 733 Italian CRC patients followed up for up to 84 months after surgery. In the Cox multivariate analysis, adjusted for gender, age, pathological stage and adjuvant chemotherapy (yes/no), the risk of death significantly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Chemotherapy, Adjuvant
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Kaplan-Meier Estimate

Share to Neoplasm Recurrence, Local

Share to Prognosis

Source

Identifiers

PMID: 25963333
DOI: 10.1038/tpj.2015.35

Genes

TTR
BMP4
GPX3
MTHFR
SMAD7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A subset of genetic susceptibility variants for colorectal cancer also has prognostic value.PMID 25963333Read ↗

Genetic susceptibility variants associated with colorectal cancer prognosis.Semantic proximity Read ↗

GWAS-identified colorectal cancer susceptibility locus associates with disease prognosis.Semantic proximity Read ↗

Colorectal cancer risk variants rs10161980 and rs7495132 are associated with cancer survival outcome by a recessive mode of inheritance.Semantic proximity Read ↗

Association of polymorphisms MTHFR C677T and A1298C with risk of colorectal cancer, genetic and epigenetic characteristic of tumors, and response to chemotherapy.Semantic proximity Read ↗

Phenotypic and tumor molecular characterization of colorectal cancer in relation to a susceptibility SMAD7 variant associated with survival.Semantic proximity Read ↗

Colorectal Cancer Risk Loci: Prognostic Factors for Clinical Outcomes? A Systematic Review and Meta-Analysis.Semantic proximity Read ↗

Association between colorectal cancer susceptibility loci and survival time after diagnosis with colorectal cancer.Semantic proximity Read ↗

Polymorphisms in the mitochondrial oxidative phosphorylation chain genes as prognostic markers for colorectal cancer.Semantic proximity Read ↗

Colorectal Cancer Risk Prediction Using the rs4939827 Polymorphism of the SMAD7 Gene in the Romanian PopulationSemantic proximity Read ↗

A retrospective observational study of the relationship between single nucleotide polymorphisms associated with the risk of developing colorectal cancer and survival.Semantic proximity Read ↗

Multiple genetic variants are associated with colorectal cancer risk in the Han Chinese population.Semantic proximity Read ↗

Colorectal cancer susceptibility loci and influence on survivalSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.