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Article

Lack of association between LIG4 gene polymorphisms and the risk of breast cancer: a HuGE review and meta-analysis.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012

Zhou Li-Ping, Luan Hong, Dong Xi-Hua, Jin Guo-Jiang, Man Dong-Liang, Shang Hong

Abstract excerpt

OBJECTIVE: Non-homologous end joining (NHEJ) is one of the pathways of repair of DNA double-strand breaks. A number of genes involved in NHEJ have been implicated as breast cancer susceptibility genes such as LIG4. However, some studies have generated conflicting results. The aim of this Human Genome Epidemiology (HuGE) review and meta-analysis was to investigate association between LIG4 gene polymorphisms in the...

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Identifiers

PMID: 22994770
DOI: 10.7314/apjcp.2012.13.7.3417

Genes

LIG4

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