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Article

Association of functional polymorphisms of the XRCC4 gene with the risk of breast cancer: a meta-analysis.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012

Zhou Li-Ping, Luan Hong, Dong Xi-Hua, Jin Guo-Jiang, Ma Dong-Liang, Shang Hong

Abstract excerpt

OBJECTIVE: X-ray cross-complementing group 4 (XRCC4) is a major repair gene for DNA double-strand breaks (DSB) in the non-homologous end-joining (NHEJ) pathway. Several potentially functional polymorphisms of the XRCC4 gene have been implicated in breast cancer risk, but individually published studies showed inconclusive results. The aim of this meta-analysis was to investigate the association between XRCC4...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22994773
DOI: 10.7314/apjcp.2012.13.7.3431

Genes

XRCC4

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