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Article

Relevance of LIG4 gene polymorphisms with cancer susceptibility: evidence from a meta-analysis.

Scientific reports - 15 Oct 2014

Xie Shang, Shan Xiao-Feng, Shang Kun, Xu Hui, He Jing, Cai Zhi-Gang

Abstract excerpt

Polymorphisms of LIG4 gene may influence DNA repair ability, thus altering the genetic stability and resulting in carcinogenesis. A growing number of studies have investigated the relevance of LIG4 T9I (rs1805388) and D501D (rs1805386) polymorphisms with cancer risk, however, the results are conflicting. To obtain a comprehensive conclusion, we searched relevant literatures from PubMed, Web of Science, Ovid and...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25314918
DOI: 10.1038/srep06630
PMCID: PMC4197418

Genes

LIG4

Variants

rs1805388
rs1805388

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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