Article
The LIG4 Ile658Val polymorphism does not affect the risk of cervical carcinoma.
Pathology, research and practice - 15 Aug 2010
Ding Zhiming, Zhang Jing, Cheng Qi, Shen Jiajie, Hu Yuting, Chen Huaizeng
Abstract excerpt
The aim of this study was to investigate whether gene LIG4 genetic polymorphism affects the risk of cervical carcinoma. We studied 500 cervical carcinoma patients and 800 normal women as controls. Demographic and epidemiologic risk factors were recorded. Single nucleotide polymorphisms (SNPs) (LIG4 Ile658Val) were genotyped. Compared to LIG4 Ile658Ile (AA) genotype, LIG4 Ile658Val (AG) did not increase or...
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